diff --git a/reg23Topograms/itkDTRrecon/CMakeLists.txt b/reg23Topograms/itkDTRrecon/CMakeLists.txt
index dff2dd7..23d2510 100644
--- a/reg23Topograms/itkDTRrecon/CMakeLists.txt
+++ b/reg23Topograms/itkDTRrecon/CMakeLists.txt
@@ -20,6 +20,7 @@ SET(SRCS
     vtkContourTopogramProjectionFilter.cxx
     DRTMetaInformation.cpp
     itkReg23.cpp
+    itkReg23MetaInformation.cpp
 )
 
 SET(HDR
@@ -31,6 +32,7 @@ SET(HDR
     vtkContourTopogramProjectionFilter.h
     DRTMetaInformation.h
     itkReg23.h
+    itkReg23MetaInformation.h
 )
 
 ADD_LIBRARY(${LIB_NAME} ${SRCS} ${HDR})
diff --git a/reg23Topograms/itkDTRrecon/DRTMetaInformation.cpp b/reg23Topograms/itkDTRrecon/DRTMetaInformation.cpp
index 0b354a3..8702d59 100644
--- a/reg23Topograms/itkDTRrecon/DRTMetaInformation.cpp
+++ b/reg23Topograms/itkDTRrecon/DRTMetaInformation.cpp
@@ -551,7 +551,6 @@ R23MetaInformation (){
     m_DegreeOfFreedom = tDegreeOfFreedomEnum::UNKNOWN;
     m_OptimizerType = tOptimizerTypeEnum::POWELL;
     m_MetricType = tMetricTypeEnum::NCC;
-    m_MaxIterations = 6;
 }
 
 
diff --git a/reg23Topograms/itkDTRrecon/DRTMetaInformation.h b/reg23Topograms/itkDTRrecon/DRTMetaInformation.h
index 6c71b5c..1aa2f5c 100644
--- a/reg23Topograms/itkDTRrecon/DRTMetaInformation.h
+++ b/reg23Topograms/itkDTRrecon/DRTMetaInformation.h
@@ -24,6 +24,13 @@ typedef enum eImageOrientationType{
     FFS = 2
 } tPatOrientation;
 
+
+typedef enum eHandlingRotImpTransform {
+    ALWAYS_USE = 0,
+    NEVER_USE,
+    STATION_DEPENDENT
+} tHandlingRotImpTransform;
+
 typedef enum eDegreeOfFreedomType {
     UNKNOWN = 0,
     THREE_DOF,
@@ -428,6 +435,11 @@ public:
     itkSetMacro(UseRotationsForHiddenTransform, bool);
     itkGetMacro(UseRotationsForHiddenTransform, bool);
 
+    itkSetEnumMacro(DegreeOfFreedom, tDegreeOfFreedomEnum);
+    itkGetEnumMacro(DegreeOfFreedom, tDegreeOfFreedomEnum);
+
+    itkSetEnumMacro(HandleRotationImpOffset, tHandlingRotImpTransform);
+    itkGetEnumMacro(HandleRotationImpOffset, tHandlingRotImpTransform);
 
 protected:
 
@@ -462,7 +474,7 @@ protected:
 
     PointType
     /* center of projection in an IEC reference at
-     * Patient Origin of fixed images. Positioning scanner */
+     * Patient Origin of fixed images. Positionin scanner */
     m_ProjectionCenter,
     m_ProjectionCenterOffset1,
     m_ProjectionCenterOffset2;
@@ -471,6 +483,12 @@ protected:
     bool
     m_UseRotationsForHiddenTransform;
 
+    tDegreeOfFreedomEnum
+    m_DegreeOfFreedom;
+
+    tHandlingRotImpTransform
+    m_HandleRotationImpOffset;
+
     /** Default Constructor **/
     DRTProjectionGeometryImageMetaInformation   ();
     /** Default Destructor **/
@@ -626,8 +644,7 @@ public:
      itkSetEnumMacro(MetricType, tMetricTypeEnum);
      itkGetEnumMacro(MetricType, tMetricTypeEnum);
 
-     itkSetEnumMacro(MaxIterations, int);
-     itkGetEnumMacro(MaxIterations, int);
+
 
 
 protected:
@@ -641,9 +658,6 @@ protected:
     tMetricTypeEnum
     m_MetricType;
 
-    int
-    m_MaxIterations;
-
     /** Default Constructor **/
     R23MetaInformation ();
     /** Default Destructor **/
diff --git a/reg23Topograms/itkDTRrecon/autoreg/itkMutualInformationTwoImageToOneImageMetric.h b/reg23Topograms/itkDTRrecon/autoreg/itkMutualInformationTwoImageToOneImageMetric.h
index 678d7c0..bed071c 100644
--- a/reg23Topograms/itkDTRrecon/autoreg/itkMutualInformationTwoImageToOneImageMetric.h
+++ b/reg23Topograms/itkDTRrecon/autoreg/itkMutualInformationTwoImageToOneImageMetric.h
@@ -95,6 +95,7 @@ public:
    * typically results in narrower valleys in the cost fucntion.
    * Default value is false. */
     itkSetMacro(SubtractMean, bool);
+    itkSetMacro(NumberOfHistogramBins, int);
     itkGetConstReferenceMacro(SubtractMean, bool);
     itkBooleanMacro(SubtractMean);
 
@@ -106,6 +107,7 @@ protected:
 
 private:
     bool m_SubtractMean;
+    int m_NumberOfHistogramBins;
 };
 
 } // end namespace itk
diff --git a/reg23Topograms/itkDTRrecon/autoreg/itkMutualInformationTwoImageToOneImageMetric.hxx b/reg23Topograms/itkDTRrecon/autoreg/itkMutualInformationTwoImageToOneImageMetric.hxx
index b7c03a7..070f6ba 100644
--- a/reg23Topograms/itkDTRrecon/autoreg/itkMutualInformationTwoImageToOneImageMetric.hxx
+++ b/reg23Topograms/itkDTRrecon/autoreg/itkMutualInformationTwoImageToOneImageMetric.hxx
@@ -36,6 +36,7 @@ MutualInformationTwoImageToOneImageMetric<TFixedImage,
     TMovingImage>::MutualInformationTwoImageToOneImageMetric()
 {
     m_SubtractMean = false;
+    m_NumberOfHistogramBins = 50;
 }
 
 template <typename TFixedImage, typename TMovingImage>
@@ -147,7 +148,8 @@ MutualInformationTwoImageToOneImageMetric<TFixedImage, TMovingImage>::GetValue()
     //auto numberOfSamples = static_cast<unsigned int>(numberOfPixels * 0.50); //100%
     // since we have a ROI, then we should not set allPixels to TRUE.
     //metric1->UseAllPixelsOn();
-    metric1->SetNumberOfHistogramBins(50);
+    std::cout << "m_NumberOfHistogramBins " << m_NumberOfHistogramBins << std::endl;
+    metric1->SetNumberOfHistogramBins(m_NumberOfHistogramBins);
 
 //    InternalImageType::IndexType pIndex;
 //    pIndex[0]=200;
@@ -183,7 +185,7 @@ MutualInformationTwoImageToOneImageMetric<TFixedImage, TMovingImage>::GetValue()
     //numberOfSamples = static_cast<unsigned int>(numberOfPixels * 0.50); //100%
     //metric2->SetNumberOfSpatialSamples(numberOfSamples);
     //metric2->UseAllPixelsOn();
-    metric2->SetNumberOfHistogramBins(50);
+    metric2->SetNumberOfHistogramBins(m_NumberOfHistogramBins);
     metric2->SetFixedImage(fixedImage2);
     metric2->SetMovingImage(this->m_Filter2->GetOutput());
     metric2->Initialize();
diff --git a/reg23Topograms/itkDTRrecon/itkImageProcessor.cpp b/reg23Topograms/itkDTRrecon/itkImageProcessor.cpp
index e8e173f..4229fca 100644
--- a/reg23Topograms/itkDTRrecon/itkImageProcessor.cpp
+++ b/reg23Topograms/itkDTRrecon/itkImageProcessor.cpp
@@ -98,6 +98,18 @@ itkImageProcessor::itkImageProcessor()
     m_r23MetaInfo = NULL;
     m_r23MetaInfo = R23MetaInformation::New();
 
+    m_PowellOptimizerMetaInfo = NULL;
+    m_PowellOptimizerMetaInfo = PowellOptimizerMetaInformation::New();
+
+    m_AmoebaOptimizerMetaInfo = NULL;
+    m_AmoebaOptimizerMetaInfo = AmoebaOptimizerMetaInformation::New();
+
+    m_MIMetricMetaInfo = NULL;
+    m_MIMetricMetaInfo = MIMetricMetaInformation::New();
+
+    m_NCCMetricMetaInfo = NULL;
+    m_NCCMetricMetaInfo = NCCMetricMetaInformation::New();
+
     /* Initialise the projection geoemtry with defaults */
     m_DRTGeometryMetaInfo = NULL;
     m_DRTGeometryMetaInfo
@@ -136,6 +148,8 @@ itkImageProcessor::itkImageProcessor()
     m_DRTGeometryMetaInfo->SetProjectionCenterOffset1(Point3D);
     m_DRTGeometryMetaInfo->SetProjectionCenterOffset2(Point3D);
 
+    m_DRTGeometryMetaInfo->SetDegreeOfFreedom(eDegreeOfFreedomType::THREE_DOF);
+    m_DRTGeometryMetaInfo->SetHandleRotationImpOffset(eHandlingRotImpTransform::ALWAYS_USE);
 
     optimizerObserver = CommandIterationUpdate::New();
     ExhaustiveOptimizerObserver = ExhaustiveCommandIterationUpdate::New();
@@ -1114,18 +1128,20 @@ itkImageProcessor::GetFinalR23Parameters(){
         break;
 
     case SIX_DOF:
-        pPars[0] = currentPosition[0]
-                - m_TransformMetaInfo->GetHiddenRotations()[0];
-        pPars[1] = currentPosition[1]
-                - m_TransformMetaInfo->GetHiddenRotations()[1];
-        pPars[2] = currentPosition[2]
-                - m_TransformMetaInfo->GetHiddenRotations()[2];
-        pPars[3] = currentPosition[3]
+        pPars[3] = currentPosition[0]
                 - m_TransformMetaInfo->GetHiddenTranslations()[0];
-        pPars[4] = currentPosition[4]
+        pPars[4] = currentPosition[1]
                 - m_TransformMetaInfo->GetHiddenTranslations()[1];
-        pPars[5] = currentPosition[5]
+        pPars[5] = currentPosition[2]
                 - m_TransformMetaInfo->GetHiddenTranslations()[2];
+
+        pPars[0] = currentPosition[3]
+                - m_TransformMetaInfo->GetHiddenRotations()[0];
+        pPars[1] = currentPosition[4]
+                - m_TransformMetaInfo->GetHiddenRotations()[1];
+        pPars[2] = currentPosition[5]
+                - m_TransformMetaInfo->GetHiddenRotations()[2];
+
         break;
 
     default:
@@ -1190,11 +1206,59 @@ void itkImageProcessor::SetMetric(std::string metric)
 
 }
 
-void itkImageProcessor::SetMaxNumberOfIterations(int iNum)
-{
-    m_r23MetaInfo->SetMaxIterations(iNum);
+void itkImageProcessor::SetDegreeOfFreedom(tDegreeOfFreedomEnum dof){
+
+    m_DRTGeometryMetaInfo->SetDegreeOfFreedom(dof);
+    m_r23MetaInfo->SetDegreeOfFreedom(dof);
+
 }
 
+void itkImageProcessor::SetHandleRotationImportOffset(eHandlingRotImpTransform hrio){
+
+    m_DRTGeometryMetaInfo->SetHandleRotationImpOffset(hrio);
+
+}
+
+
+
+void itkImageProcessor::SetPowellOptimParameters(
+        double dStepT,
+        double dValTol,
+        double dStepL,
+        int iMaxLinI,
+        int iMaxIter){
+
+    m_PowellOptimizerMetaInfo->SetStepTolerance(dStepT);
+    m_PowellOptimizerMetaInfo->SetValueTolerance(dValTol);
+    m_PowellOptimizerMetaInfo->SetStepLength(dStepL);
+    m_PowellOptimizerMetaInfo->SetMaximumLineInteration(iMaxLinI);
+    m_PowellOptimizerMetaInfo->SetMaxIterations(iMaxIter);
+
+}
+
+void itkImageProcessor::SetAmoebaOptimParameters(
+        double dParConvTol,
+        double dFuntConvTol,
+        double dSimplex,
+        int iMaxIter){
+    m_AmoebaOptimizerMetaInfo->SetParametersConvergenceTolerance(dParConvTol);
+    m_AmoebaOptimizerMetaInfo->SetFunctionConvergenceTolerance(dFuntConvTol);
+    m_AmoebaOptimizerMetaInfo->SetSimplexDelta(dSimplex);
+    m_AmoebaOptimizerMetaInfo->SetMaxIterations(iMaxIter);
+
+}
+
+void itkImageProcessor::SetMIMetricParameters(double dMaxT,int iNhb){
+    m_MIMetricMetaInfo->SetMaxTranslation(dMaxT);
+    m_MIMetricMetaInfo->SetNumberOfHistogramBins(iNhb);
+}
+
+void itkImageProcessor::SetNCCMetricParameters(double dMaxT,bool bSm){
+    m_NCCMetricMetaInfo->SetMaxTranslation(dMaxT);
+    m_NCCMetricMetaInfo->SetSubtractMean(bSm);
+}
+
+
 void itkImageProcessor::InitializeProjector()
 {
 
@@ -2523,15 +2587,18 @@ void itkImageProcessor::ResetROIRegions(){
 
 }
 
-void itkImageProcessor::InizializeRegistration(double stepLength,
-                            double maxTranslation,
-                            eDegreeOfFreedomType dof){
+void itkImageProcessor::InizializeRegistration(){
 
-    m_r23MetaInfo->SetDegreeOfFreedom(dof);
     m_R23->SetPA(m_PASourceDupli->GetOutput());
     m_R23->SetLAT(m_LATSourceDupli->GetOutput());
     m_R23->SetVolume(m_VolumeSourceDupli->GetOutput());
+
     m_R23->Setr23Meta(m_r23MetaInfo);
+    m_R23->SetPowellMeta(m_PowellOptimizerMetaInfo);
+    m_R23->SetAmoebaMeta(m_AmoebaOptimizerMetaInfo);
+    m_R23->SetMIMeta(m_MIMetricMetaInfo);
+    m_R23->SetNCCMeta(m_NCCMetricMetaInfo);
+
     m_R23->SetInternalTransf1(m_InternalTransf1);
     m_R23->SetInternalTransf2(m_InternalTransf2);
     m_R23->Setfilter1(filter1);
@@ -2540,8 +2607,7 @@ void itkImageProcessor::InizializeRegistration(double stepLength,
     m_R23->Setinterpolator2(interpolator2);
     m_R23->SetTransformMetaInfo(m_TransformMetaInfo);
 
-    m_R23->InitializeRegistration(
-                stepLength,maxTranslation,dof);
+    m_R23->InitializeRegistration();
 
 }
 
diff --git a/reg23Topograms/itkDTRrecon/itkImageProcessor.h b/reg23Topograms/itkDTRrecon/itkImageProcessor.h
index cb7b22d..8939750 100644
--- a/reg23Topograms/itkDTRrecon/itkImageProcessor.h
+++ b/reg23Topograms/itkDTRrecon/itkImageProcessor.h
@@ -47,6 +47,7 @@ gfattori 08.11.2021
 #include "itkImageProcessorHelpers.h"
 
 #include "itkReg23.h"
+#include "itkReg23MetaInformation.h"
 
 namespace itk
 {
@@ -86,12 +87,9 @@ public:
     void SetRegionFixed1(int,int,int,int);
     void SetRegionFixed2(int,int,int,int);
     void ResetROIRegions();
-    void InizializeRegistration(double stepLength,
-                                double maxTranslation,
-                                eDegreeOfFreedomType dof);
+    void InizializeRegistration();
 
     /** Maximum number of iterations for the optimizer */
-    void SetMaxNumberOfIterations(int);
     itkGetMacro(R23, itkReg23::Pointer);
 
 
@@ -103,6 +101,24 @@ public:
     void SetMetric(std::string);
     void SetMetric(tMetricTypeEnum);
 
+    /** Set DOF */
+    void SetDegreeOfFreedom(tDegreeOfFreedomEnum);
+
+    /** Set Handle Of Rotation Import Offset */
+    void SetHandleRotationImportOffset(tHandlingRotImpTransform);
+
+    /** Set PowellOptimizer */
+    void SetPowellOptimParameters(double,double,double,int,int);
+
+    /** Set AmoebaOptimizer */
+    void SetAmoebaOptimParameters(double,double,double,int);
+
+    /** Set MI */
+    void SetMIMetricParameters(double,int);
+
+    /** Set NCC */
+    void SetNCCMetricParameters(double,bool);
+
     /** Set number of logic CPU to be made available to interpolators*/
     void SetNumberOfWorkingUnits(int iN);
 
@@ -390,6 +406,18 @@ private:
     R23MetaInformation::Pointer
     m_r23MetaInfo;
 
+    PowellOptimizerMetaInformation::Pointer
+    m_PowellOptimizerMetaInfo;
+
+    AmoebaOptimizerMetaInformation::Pointer
+    m_AmoebaOptimizerMetaInfo;
+
+    MIMetricMetaInformation::Pointer
+    m_MIMetricMetaInfo;
+
+    NCCMetricMetaInformation::Pointer
+    m_NCCMetricMetaInfo;
+
     InternalTransformMetaInformation::Pointer
     m_InternalTransf1,
     m_InternalTransf2;
diff --git a/reg23Topograms/itkDTRrecon/itkImageProcessorHelpers.cpp b/reg23Topograms/itkDTRrecon/itkImageProcessorHelpers.cpp
index bb93324..8d0760b 100644
--- a/reg23Topograms/itkDTRrecon/itkImageProcessorHelpers.cpp
+++ b/reg23Topograms/itkDTRrecon/itkImageProcessorHelpers.cpp
@@ -100,6 +100,7 @@ CalculateInternalTransformV3(
 const char* queryStationName(const char* pcFName){
 
     static std::string buffer;
+    buffer.clear();
 
     /* Check if we can open the file */
     gdcm::Reader R;
@@ -112,10 +113,8 @@ const char* queryStationName(const char* pcFName){
     const gdcm::File &file = R.GetFile();
     const gdcm::DataSet &ds = file.GetDataSet();
 
-    std::string s (gGetStringValueFromTag(gdcm::Tag(0x0008,0x1010), ds));
-    std::copy(s.rbegin(), s.rend(), std::back_inserter(buffer));
-
-    std::reverse(buffer.begin(),buffer.end());
+    std::string s(gGetStringValueFromTag(gdcm::Tag(0x0008,0x1010), ds));
+    std::copy(s.begin(), s.end(), buffer.begin());
 
     return buffer.c_str();
 
@@ -134,10 +133,12 @@ int query2DimageReconstructionDiameter(const char *pcFName){
     const gdcm::File &file = R.GetFile();
     const gdcm::DataSet &ds = file.GetDataSet();
 
-    char* sTmpString = new char [255];
-    strcpy( sTmpString,gGetStringValueFromTag(gdcm::Tag(0x0018,0x1100), ds));
+    std::string buffer;
 
-    return std::atoi(sTmpString);
+    std::string s(gGetStringValueFromTag(gdcm::Tag(0x0018,0x1100), ds));
+    std::copy(s.begin(), s.end(), buffer.begin());
+
+    return std::stoi(buffer);
 }
 
 
diff --git a/reg23Topograms/itkDTRrecon/itkReg23.cpp b/reg23Topograms/itkDTRrecon/itkReg23.cpp
index 85c81c1..4ba0e29 100644
--- a/reg23Topograms/itkDTRrecon/itkReg23.cpp
+++ b/reg23Topograms/itkDTRrecon/itkReg23.cpp
@@ -13,6 +13,7 @@ itkReg23::itkReg23()
     NCCmetric = MetricType::New();
     MImetric = MIMetricType::New();
 
+
     // Optimizers
     PowellOptimizer = PowellOptimizerType::New();
     AmoebaOptimizer = AmoebaOptimizerType::New();
@@ -71,10 +72,7 @@ void itkReg23::PrintSelf(std::ostream& os, Indent indent) const
     Superclass::PrintSelf(os, indent);
 }
 
-void itkReg23::InitializeRegistration(
-        double stepLength,
-        double maxTranslation,
-        eDegreeOfFreedomType dof)
+void itkReg23::InitializeRegistration()
 {
     std::cout << "*" << __COMPACT_PRETTY_FUNCTION__ << std::endl;
 
@@ -126,6 +124,17 @@ void itkReg23::InitializeRegistration(
         itkExceptionMacro(<< "m_interpolator2 data not present");
     }
 
+//    std::cout << "Print r23" <<
+//                 m_r23Meta->GetMetricType() << " " << m_r23Meta->GetDegreeOfFreedom() <<  std::endl;
+//    std::cout << "Print Powell" <<
+//                 m_PowellMeta->GetStepLength() << " " << m_PowellMeta->GetStepTolerance() <<  std::endl;
+//    std::cout << "Print Amoeba" <<
+//                m_AmoebaMeta->GetFunctionConvergenceTolerance() << " " << m_AmoebaMeta->GetSimplexDelta() <<  std::endl;
+//    std::cout << "Print NCC" <<
+//                m_NCCMeta->GetSubtractMean() << " " << m_NCCMeta->GetMaxTranslation() <<  std::endl;
+//    std::cout << "Print MI" <<
+//                 m_MIMeta->GetMaxTranslation() <<  std::endl;
+
     AmoebaOptimizerType::ParametersType simplexDelta(3);
     ExhaustiveOptimizerType::StepsType steps(3);
     const int numberOfSteps = 25; //In each direction. Total number of steps is ((2*numberOfSteps+1))^3. For 25 -> 132651.
@@ -137,11 +146,11 @@ void itkReg23::InitializeRegistration(
         std::cout<< "Using POWELL Optimizer" <<std::endl;
 
         PowellOptimizer->SetMaximize(false); // for NCC and MI
-        PowellOptimizer->SetMaximumIteration(m_r23Meta->GetMaxIterations());
-        PowellOptimizer->SetMaximumLineIteration(4); // for Powell's method
-        PowellOptimizer->SetStepLength(stepLength);
-        PowellOptimizer->SetStepTolerance(0.01);
-        PowellOptimizer->SetValueTolerance(0.000002);
+        PowellOptimizer->SetMaximumIteration(m_PowellMeta->GetMaxIterations());
+        PowellOptimizer->SetMaximumLineIteration(m_PowellMeta->GetMaximumLineInteration()); // for Powell's method
+        PowellOptimizer->SetStepLength(m_PowellMeta->GetStepLength());
+        PowellOptimizer->SetStepTolerance(m_PowellMeta->GetStepTolerance());
+        PowellOptimizer->SetValueTolerance(m_PowellMeta->GetValueTolerance());
         PowellOptimizer->RemoveAllObservers();
         PowellOptimizer->AddObserver(itk::IterationEvent(), m_OptimizerObserver);
 
@@ -153,17 +162,17 @@ void itkReg23::InitializeRegistration(
         std::cout<< "Using AMOEBA Optimizer" <<std::endl;
 
         AmoebaOptimizer->SetMinimize(true);
-        AmoebaOptimizer->SetMaximumNumberOfIterations(m_r23Meta->GetMaxIterations());
-        AmoebaOptimizer->SetParametersConvergenceTolerance(0.1);
-        AmoebaOptimizer->SetFunctionConvergenceTolerance(0.000002);
+        AmoebaOptimizer->SetMaximumNumberOfIterations(m_AmoebaMeta->GetMaxIterations());
+        AmoebaOptimizer->SetParametersConvergenceTolerance(m_AmoebaMeta->GetParametersConvergenceTolerance());
+        AmoebaOptimizer->SetFunctionConvergenceTolerance(m_AmoebaMeta->GetFunctionConvergenceTolerance());
         AmoebaOptimizer->SetAutomaticInitialSimplex(false);
         //Initial size of the simplex (otherwise it is a very small number and optimizer stops immeditaly)
         // 2 mm / 2 degrees seems to be a good value which performs well.
-        if (GetNumberOfDOF(dof) == 0) {
+        if (GetNumberOfDOF(m_r23Meta->GetDegreeOfFreedom()) == 0) {
             itkExceptionMacro(<< "Unkown or unsupported degree of freedom");
         }
-        for (int i = 0; i < GetNumberOfDOF(dof); i++) {
-            simplexDelta[i] = 2.0;
+        for (int i = 0; i < GetNumberOfDOF(m_r23Meta->GetDegreeOfFreedom()); i++) {
+            simplexDelta[i] = m_AmoebaMeta->GetSimplexDelta();
         }
         AmoebaOptimizer->SetInitialSimplexDelta(simplexDelta);
         AmoebaOptimizer->RemoveAllObservers();
@@ -176,13 +185,13 @@ void itkReg23::InitializeRegistration(
     case tOptimizerTypeEnum::EXHAUSTIVE:
         std::cout<< "Using Extensive Optimizer" <<std::endl;
 
-        steps[0] = numberOfSteps;
-        steps[1] = numberOfSteps;
-        steps[2] = numberOfSteps;
-        ExhaustiveOptimizer->SetNumberOfSteps(steps);
-        ExhaustiveOptimizer->SetStepLength(stepLength);
+//        steps[0] = numberOfSteps;
+//        steps[1] = numberOfSteps;
+//        steps[2] = numberOfSteps;
+//        ExhaustiveOptimizer->SetNumberOfSteps(steps);
+//        ExhaustiveOptimizer->SetStepLength(stepLength);
 
-        registration->SetOptimizer(ExhaustiveOptimizer);
+//        registration->SetOptimizer(ExhaustiveOptimizer);
 
         break;
 
@@ -197,8 +206,9 @@ void itkReg23::InitializeRegistration(
         std::cout<< "Using MI Metric" <<std::endl;
 
         registration->SetMetric(MImetric);
+        MImetric->SetNumberOfHistogramBins(m_MIMeta->GetNumberOfHistogramBins());
         MImetric->ComputeGradientOff();
-        MImetric->SetMaxTranslation(maxTranslation);
+        MImetric->SetMaxTranslation(m_MIMeta->GetMaxTranslation());
 
         break;
 
@@ -207,7 +217,7 @@ void itkReg23::InitializeRegistration(
         registration->SetMetric(NCCmetric);
         NCCmetric->ComputeGradientOff();
         NCCmetric->SetSubtractMean(true);
-        NCCmetric->SetMaxTranslation(maxTranslation);
+        NCCmetric->SetMaxTranslation(m_NCCMeta->GetMaxTranslation());
 
         break;
 
diff --git a/reg23Topograms/itkDTRrecon/itkReg23.h b/reg23Topograms/itkDTRrecon/itkReg23.h
index f885cc0..1a6f62e 100644
--- a/reg23Topograms/itkDTRrecon/itkReg23.h
+++ b/reg23Topograms/itkDTRrecon/itkReg23.h
@@ -18,6 +18,8 @@
 #include "itkImageProcessorHelpers.h"
 #include "itkQtIterationUpdate.h"
 
+#include "itkReg23MetaInformation.h"
+
 
 namespace itk{
 
@@ -50,6 +52,19 @@ public:
     itkSetMacro(r23Meta, R23MetaInformation::Pointer);
     itkGetMacro(r23Meta, R23MetaInformation::Pointer);
 
+    itkSetMacro(PowellMeta, PowellOptimizerMetaInformation::Pointer);
+    itkGetMacro(PowellMeta, PowellOptimizerMetaInformation::Pointer);
+
+    itkSetMacro(AmoebaMeta, AmoebaOptimizerMetaInformation::Pointer);
+    itkGetMacro(AmoebaMeta, AmoebaOptimizerMetaInformation::Pointer);
+
+    itkSetMacro(MIMeta, MIMetricMetaInformation::Pointer);
+    itkGetMacro(MIMeta, MIMetricMetaInformation::Pointer);
+
+    itkSetMacro(NCCMeta, NCCMetricMetaInformation::Pointer);
+    itkGetMacro(NCCMeta, NCCMetricMetaInformation::Pointer);
+
+
     itkSetMacro(Volume, InternalImageType::Pointer);
     itkGetMacro(Volume, InternalImageType::Pointer);
 
@@ -92,9 +107,7 @@ public:
     /** Auto Reg23 methods */
 
     /** Initialize the registration pipeline*/
-    void InitializeRegistration(double stepLength,
-                                double maxTranslation,
-                                eDegreeOfFreedomType dof);
+    void InitializeRegistration();
     /** Start the registration process*/
     int StartRegistration(std::string extraInfo);
     /** Get the current cost function value from the optimizer*/
@@ -151,6 +164,18 @@ private:
     R23MetaInformation::Pointer
     m_r23Meta;
 
+    PowellOptimizerMetaInformation::Pointer
+    m_PowellMeta;
+
+    AmoebaOptimizerMetaInformation::Pointer
+    m_AmoebaMeta;
+
+    MIMetricMetaInformation::Pointer
+    m_MIMeta;
+
+    NCCMetricMetaInformation::Pointer
+    m_NCCMeta;
+
     InternalImageType::Pointer
     m_Volume,
     m_PA,
diff --git a/reg23Topograms/itkDTRrecon/itkReg23MetaInformation.cpp b/reg23Topograms/itkDTRrecon/itkReg23MetaInformation.cpp
new file mode 100644
index 0000000..32d94a7
--- /dev/null
+++ b/reg23Topograms/itkDTRrecon/itkReg23MetaInformation.cpp
@@ -0,0 +1,104 @@
+#include "itkReg23MetaInformation.h"
+
+
+namespace itk {
+
+PowellOptimizerMetaInformation::
+PowellOptimizerMetaInformation(){
+
+    this->m_MaximumLineInteration = 4;
+    this->m_StepLength = 2.0;
+    this->m_StepTolerance = 0.01;
+    this->m_ValueTolerance = 0.000002;
+
+    this->m_MaxIterations = 6;
+}
+
+void
+PowellOptimizerMetaInformation
+::PrintSelf(std::ostream& os, itk::Indent indent) const
+{
+    Superclass::PrintSelf(os, indent);
+}
+
+
+PowellOptimizerMetaInformation
+::~PowellOptimizerMetaInformation ()
+{
+
+}
+
+
+AmoebaOptimizerMetaInformation::
+AmoebaOptimizerMetaInformation(){
+
+    this->m_ParametersConvergenceTolerance = 0.1;
+    this->m_FunctionConvergenceTolerance = 0.000002;
+    this->m_SimplexDelta = 2.0;
+
+    this->m_MaxIterations = 100;
+}
+
+
+void
+AmoebaOptimizerMetaInformation
+::PrintSelf(std::ostream& os, itk::Indent indent) const
+{
+    Superclass::PrintSelf(os, indent);
+}
+
+
+AmoebaOptimizerMetaInformation
+::~AmoebaOptimizerMetaInformation ()
+{
+
+}
+
+
+MIMetricMetaInformation::
+MIMetricMetaInformation(){
+
+    this->m_MaxTranslation = 100.0;
+    this->m_NumberOfHistogramBins = 50;
+
+}
+
+
+void
+MIMetricMetaInformation
+::PrintSelf(std::ostream& os, itk::Indent indent) const
+{
+    Superclass::PrintSelf(os, indent);
+}
+
+
+MIMetricMetaInformation
+::~MIMetricMetaInformation ()
+{
+
+}
+
+NCCMetricMetaInformation::
+NCCMetricMetaInformation(){
+
+    this->m_MaxTranslation = 100.0;
+    this->m_SubtractMean = true;
+
+}
+
+
+void
+NCCMetricMetaInformation
+::PrintSelf(std::ostream& os, itk::Indent indent) const
+{
+    Superclass::PrintSelf(os, indent);
+}
+
+
+NCCMetricMetaInformation
+::~NCCMetricMetaInformation ()
+{
+
+}
+
+}
diff --git a/reg23Topograms/itkDTRrecon/itkReg23MetaInformation.h b/reg23Topograms/itkDTRrecon/itkReg23MetaInformation.h
new file mode 100644
index 0000000..45d1c5c
--- /dev/null
+++ b/reg23Topograms/itkDTRrecon/itkReg23MetaInformation.h
@@ -0,0 +1,232 @@
+#ifndef ITKREG23METAINFORMATION_H
+#define ITKREG23METAINFORMATION_H
+
+#include "itkObject.h"
+#include "itkObjectFactory.h"
+#include "itkSmartPointer.h"
+#include "itkMacro.h"
+
+
+namespace itk {
+
+
+class PowellOptimizerMetaInformation :
+        public itk::Object{
+
+public:
+    /** standard typedefs **/
+    typedef PowellOptimizerMetaInformation  Self;
+    typedef itk::Object Superclass;
+    typedef itk::SmartPointer<Self> Pointer;
+
+    /** Method for creation through the object factory. */
+    itkNewMacro(Self);
+
+    /** Run-time type information (and related methods). */
+    itkTypeMacro(PowellOptimizerMetaInformation, itk::Object);
+
+    /** object information streaming **/
+    void PrintSelf(std::ostream& os, itk::Indent indent) const;
+
+
+    itkSetMacro(StepTolerance,double);
+    itkGetMacro(StepTolerance,double);
+
+    itkSetMacro(ValueTolerance,double);
+    itkGetMacro(ValueTolerance,double);
+
+    itkSetMacro(StepLength,double);
+    itkGetMacro(StepLength,double);
+
+    itkSetMacro(MaximumLineInteration,int);
+    itkGetMacro(MaximumLineInteration,int);
+
+    itkSetEnumMacro(MaxIterations, int);
+    itkGetEnumMacro(MaxIterations, int);
+
+
+protected:
+
+    double m_StepTolerance;
+
+    double m_ValueTolerance;
+
+    double m_StepLength;
+
+    int m_MaximumLineInteration;
+
+    int
+    m_MaxIterations;
+
+    /** Default Constructor **/
+    PowellOptimizerMetaInformation  ();
+    /** Default Destructor **/
+    virtual ~PowellOptimizerMetaInformation  ();
+
+private:
+    /** purposely not implemented **/
+    PowellOptimizerMetaInformation (const Self&);
+
+    /** purposely not implemented **/
+    void operator=(const Self&);
+};
+
+
+class AmoebaOptimizerMetaInformation :
+        public itk::Object{
+
+public:
+    /** standard typedefs **/
+    typedef AmoebaOptimizerMetaInformation  Self;
+    typedef itk::Object Superclass;
+    typedef itk::SmartPointer<Self> Pointer;
+
+    /** Method for creation through the object factory. */
+    itkNewMacro(Self);
+
+    /** Run-time type information (and related methods). */
+    itkTypeMacro(AmoebaOptimizerMetaInformation, itk::Object);
+
+    /** object information streaming **/
+    void PrintSelf(std::ostream& os, itk::Indent indent) const;
+
+
+    itkSetMacro(ParametersConvergenceTolerance,double);
+    itkGetMacro(ParametersConvergenceTolerance,double);
+
+    itkSetMacro(FunctionConvergenceTolerance,double);
+    itkGetMacro(FunctionConvergenceTolerance,double);
+
+    itkSetMacro(SimplexDelta,double);
+    itkGetMacro(SimplexDelta,double);
+
+    itkSetEnumMacro(MaxIterations, int);
+    itkGetEnumMacro(MaxIterations, int);
+
+protected:
+
+    double m_ParametersConvergenceTolerance;
+
+    double m_FunctionConvergenceTolerance;
+
+    double m_SimplexDelta;
+
+    int
+    m_MaxIterations;
+
+    /** Default Constructor **/
+    AmoebaOptimizerMetaInformation  ();
+    /** Default Destructor **/
+    virtual ~AmoebaOptimizerMetaInformation  ();
+
+private:
+    /** purposely not implemented **/
+    AmoebaOptimizerMetaInformation (const Self&);
+
+    /** purposely not implemented **/
+    void operator=(const Self&);
+};
+
+
+class MIMetricMetaInformation :
+        public itk::Object{
+
+public:
+    /** standard typedefs **/
+    typedef MIMetricMetaInformation  Self;
+    typedef itk::Object Superclass;
+    typedef itk::SmartPointer<Self> Pointer;
+
+    /** Method for creation through the object factory. */
+    itkNewMacro(Self);
+
+    /** Run-time type information (and related methods). */
+    itkTypeMacro(MIMetricMetaInformation, itk::Object);
+
+    /** object information streaming **/
+    void PrintSelf(std::ostream& os, itk::Indent indent) const;
+
+
+    itkSetMacro(MaxTranslation,double);
+    itkGetMacro(MaxTranslation,double);
+
+    itkSetMacro(NumberOfHistogramBins,int);
+    itkGetMacro(NumberOfHistogramBins,int);
+
+protected:
+
+    double m_MaxTranslation;
+
+    int m_NumberOfHistogramBins;
+
+
+    /** Default Constructor **/
+    MIMetricMetaInformation  ();
+    /** Default Destructor **/
+    virtual ~MIMetricMetaInformation  ();
+
+private:
+    /** purposely not implemented **/
+    MIMetricMetaInformation (const Self&);
+
+    /** purposely not implemented **/
+    void operator=(const Self&);
+};
+
+
+class NCCMetricMetaInformation :
+        public itk::Object{
+
+public:
+    /** standard typedefs **/
+    typedef NCCMetricMetaInformation  Self;
+    typedef itk::Object Superclass;
+    typedef itk::SmartPointer<Self> Pointer;
+
+    /** Method for creation through the object factory. */
+    itkNewMacro(Self);
+
+    /** Run-time type information (and related methods). */
+    itkTypeMacro(NCCMetricMetaInformation, itk::Object);
+
+    /** object information streaming **/
+    void PrintSelf(std::ostream& os, itk::Indent indent) const;
+
+
+    itkSetMacro(MaxTranslation,double);
+    itkGetMacro(MaxTranslation,double);
+
+    itkSetMacro(SubtractMean,bool);
+    itkGetMacro(SubtractMean,bool);
+
+protected:
+
+    double m_MaxTranslation;
+
+    bool m_SubtractMean;
+
+
+
+    /** Default Constructor **/
+    NCCMetricMetaInformation  ();
+    /** Default Destructor **/
+    virtual ~NCCMetricMetaInformation  ();
+
+private:
+    /** purposely not implemented **/
+    NCCMetricMetaInformation (const Self&);
+
+    /** purposely not implemented **/
+    void operator=(const Self&);
+};
+
+}
+
+
+
+
+
+
+
+
+#endif