diff --git a/configure/RULES_TOP b/configure/RULES_TOP
index 838994bd0..b18fbf026 100644
--- a/configure/RULES_TOP
+++ b/configure/RULES_TOP
@@ -15,6 +15,10 @@ CVSCLEAN = $(call FIND_TOOL,cvsclean.pl)
 cvsclean:
 	$(PERL) $(CVSCLEAN)
 
+DEPCLEAN = $(call FIND_TOOL,depclean.pl)
+depclean:
+	$(PERL) $(DEPCLEAN)
+
 realuninstall: uninstallDirs
 	$(RMDIR) $(INSTALL_LOCATION_BIN)
 	$(RMDIR) $(INSTALL_LOCATION_LIB)
@@ -73,12 +77,14 @@ help:
 	@echo "     uninstall      - Remove install directories created by this hostarch."
 	@echo "     realuninstall  - Removes ALL install dirs"
 	@echo "     distclean      - Same as realclean cvsclean realuninstall."
+	@echo "     depclean       - Removes all .d files from O.<arch> directories."
 	@echo "     cvsclean       - Removes cvs .#* files in all dirs of directory tree"
 	@echo "     help           - Prints this list of valid make targets "
 	@echo "Indiv. object targets are supported by O.<arch> level Makefile .e.g"
 	@echo "     xxxRecord.o"
 
-.PHONY: cleandirs distclean cvsclean realuninstall archuninstall uninstallDirs
+.PHONY: cleandirs distclean cvsclean depclean
+.PHONY: realuninstall archuninstall uninstallDirs
 .PHONY: uninstall help
 
 # Include <top>/cfg/TOP_RULES* files from tops defined in RELEASE* files
diff --git a/src/tools/Makefile b/src/tools/Makefile
index d07092271..b7d6582cb 100644
--- a/src/tools/Makefile
+++ b/src/tools/Makefile
@@ -20,6 +20,7 @@ PERL_MODULES += EPICS/Getopts.pm
 PERL_SCRIPTS += assembleSnippets.pl
 PERL_SCRIPTS += convertRelease.pl
 PERL_SCRIPTS += cvsclean.pl
+PERL_SCRIPTS += depclean.pl
 PERL_SCRIPTS += dos2unix.pl
 PERL_SCRIPTS += expandVars.pl
 PERL_SCRIPTS += fullPathName.pl
diff --git a/src/tools/depclean.pl b/src/tools/depclean.pl
new file mode 100644
index 000000000..cbf6077d1
--- /dev/null
+++ b/src/tools/depclean.pl
@@ -0,0 +1,20 @@
+#!/usr/bin/env perl
+#*************************************************************************
+# Copyright (c) 2018 UChicago Argonne LLC, as Operator of Argonne
+# National Laboratory.
+# This file is distributed subject to a Software License Agreement found
+# in the file LICENSE that is included with this distribution.
+#*************************************************************************
+
+# Find and delete dependency files from all build dirs in the source tree.
+# The extension for dependency files is assumed to be .d (currently true).
+
+use File::Find;
+
+@ARGV = ('.') unless @ARGV;
+
+sub check {
+    unlink if -f && m(/O\.[^/]+/[^/]+\.d$);
+}
+
+find({ wanted => \&check, no_chdir => 1 }, @ARGV);